Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D<sub>2</sub> Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor

The interplay between the dopamine (DA) and opioid systems in the brain is known to modulate the additive effects of substances of abuse. On one hand, opioids serve mankind by their analgesic properties, which are mediated via the mu opioid receptor (MOR), a Class A G protein-coupled receptor (GPCR)...

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Bibliographic Details
Main Authors: Lakshmi Vasudevan, Dasiel O. Borroto-Escuela, Jelle Huysentruyt, Kjell Fuxe, Deepak K. Saini, Christophe Stove
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/8/368