The Role of Toll-like Receptor-4 in Macrophage Imbalance in Lethal COVID-19 Lung Disease, and Its Correlation with Galectin-3

The Role of Toll-like Receptor-4 in Macrophage Imbalance in Lethal COVID-19 Lung Disease, and Its Correlation with Galectin-3

To the current data, there have been 6,955,141 COVID-19-related deaths worldwide, reported to WHO. Toll-like receptors (TLRs) implicated in bacterial and virus sensing could be a crosstalk between activation of persistent innate-immune inflammation, and macrophage’s sub-population alterations, impli...

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Bibliographic Details
Main Authors: Maria Carmela Pedicillo, Ilenia Sara De Stefano, Rosanna Zamparese, Raffaele Barile, Mario Meccariello, Alessio Agostinone, Giuliana Villani, Tommaso Colangelo, Gaetano Serviddio, Tommaso Cassano, Andrea Ronchi, Renato Franco, Paola Pannone, Federica Zito Marino, Francesco Miele, Maurizio Municinò, Giuseppe Pannone
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
TLRs
TLR-4
SARS-CoV-2
lethal COVID-19
lung disease
macrophage shift
Online Access:https://www.mdpi.com/1422-0067/24/17/13259

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https://www.mdpi.com/1422-0067/24/17/13259

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