Macrophage Sprouty4 deficiency diminishes sepsis-induced acute lung injury in mice

Macrophage Sprouty4 deficiency diminishes sepsis-induced acute lung injury in mice

Objective: Inflammation and oxidative stress play critical roles in sepsis-induced acute lung injury (ALI). Sprout4 (Spry4) is involved in regulating inflammation and tissue injury; however, its role and mechanism in sepsis-induced ALI remain elusive. Methods: Macrophage-specific Spry4 knockout (Spr...

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Bibliographic Details
Main Authors: Rong Chen, Chen Cao, Huimin Liu, Wanli Jiang, Rui Pan, He He, Ke Ding, Qingtao Meng
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Redox Biology
Subjects:
Acute lung injury
AMPK
Inflammation
Oxidative stress
Sprouty4
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002853

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http://www.sciencedirect.com/science/article/pii/S2213231722002853

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