Concurrent Determination of Tigecycline, Tetracyclines and Their 4-Epimer Derivatives in Chicken Muscle Isolated from a Reversed-Phase Chromatography System Using Tandem Mass Spectrometry

Concurrent Determination of Tigecycline, Tetracyclines and Their 4-Epimer Derivatives in Chicken Muscle Isolated from a Reversed-Phase Chromatography System Using Tandem Mass Spectrometry

A quantitative and qualitative method using a high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) detection approach was developed and validated for the analysis of tigecycline, four tetracyclines and their three 4-epimer derivatives in chicken muscle. Samples were extracted...

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Bibliographic Details
Main Authors: Yawen Guo, Zhaoyuan He, Pengfei Gao, Shuyu Liu, Yali Zhu, Kaizhou Xie, Yuhao Dong
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
tigecycline
tetracyclines
residues
reversed-phase column
HPLC–MS/MS
Online Access:https://www.mdpi.com/1420-3049/27/19/6139

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https://www.mdpi.com/1420-3049/27/19/6139

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