XBP1 impacts lung adenocarcinoma progression by promoting plasma cell adaptation to the tumor microenvironment

XBP1 impacts lung adenocarcinoma progression by promoting plasma cell adaptation to the tumor microenvironment

Background: The activation of X-box binding protein 1 (XBP1) plays an essential role in the unfolded protein response (UPR) of the endoplasmic reticulum (ER). XBP1 is commonly expressed in various tumors and is closely related to tumorigenesis and progression. However, the role of XBP1 in lung adeno...

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Bibliographic Details
Main Authors: Zhaoqian Zhong, Junhao Wang, Qizheng Han, Hong Lin, Haihua Luo, Danyan Guo, Yong Jiang, Aihua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
x-box binding protein 1
lung adenocarcinoma
tumor microenvironment
plasma cells
alternative splicing
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.969536/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.969536/full

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