Anti-MOG autoantibodies pathogenicity in children and macaques demyelinating diseases

Anti-MOG autoantibodies pathogenicity in children and macaques demyelinating diseases

Abstract Background Autoantibodies against myelin oligodendrocyte glycoprotein (anti-MOG-Abs) occur in a majority of children with acquired demyelinating syndromes (ADS) and physiopathology is still under investigation. As cynomolgus macaques immunized with rhMOG, all develop an experimental autoimm...

Full description

Bibliographic Details
Main Authors: Che Serguera, Lev Stimmer, Claire-Maelle Fovet, Philippe Horellou, Vanessa Contreras, Nicolas Tchitchek, Julie Massonneau, Carole Leroy, Audrey Perrin, Julien Flament, Philippe Hantraye, Joanna Demilly, Romain Marignier, Pascale Chrétien, Bert‘t Hart, Jean Boutonnat, Clovis Adam, Roger Le-Grand, Kumaran Deiva
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Anti-MOG IgG
Cytokines
Complement
Demyelination
Brain inflammation
CSF
Online Access:https://doi.org/10.1186/s12974-019-1637-7

Internet

https://doi.org/10.1186/s12974-019-1637-7

Similar Items