Alpha-synuclein oligomers and small nerve fiber pathology in skin are potential biomarkers of Parkinson’s disease
Abstract The proximity ligation assay (PLA) is a specific and sensitive technique for the detection of αSyn oligomers (αSyn-PLA), early and toxic species implicated in the pathogenesis of PD. We aimed to evaluate by skin biopsy the diagnostic and prognostic capacity of αSyn-PLA and small nerve fiber...
| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Nature Portfolio
2021-12-01
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| シリーズ: | npj Parkinson's Disease |
| オンライン･アクセス: | https://doi.org/10.1038/s41531-021-00262-y |