Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis

Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis

Inflammation and oxidative stress are common and co-substantial pathological processes accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β-catenin pathway and peroxisome proliferator-activated receptor gamma (PPARγ) generally work in opposition. If one of them is upreg...

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Bibliographic Details
Main Authors: Alexandre Vallée, Yves Lecarpentier
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
canonical WNT/β-catenin pathway
PPARγ
carcinogenesis
chronic inflammation
oxidative stress
reactive oxygen species
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00745/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00745/full

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