Estrogen Receptor Beta (ERβ): A Ligand Activated Tumor Suppressor

Estrogen Receptor Beta (ERβ): A Ligand Activated Tumor Suppressor

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize and translocate to the nucleus where they activate or repress the transcription of a large number of genes, thus modulati...

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Bibliographic Details
Main Authors: Rahul Mal, Alexa Magner, Joel David, Jharna Datta, Meghna Vallabhaneni, Mahmoud Kassem, Jasmine Manouchehri, Natalie Willingham, Daniel Stover, Jeffery Vandeusen, Sagar Sardesai, Nicole Williams, Robert Wesolowski, Maryam Lustberg, Ramesh K. Ganju, Bhuvaneswari Ramaswamy, Mathew A. Cherian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
ESR1
ESR2
ERα
ERβ
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.587386/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.587386/full

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