TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits

TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits

Myelin repair in the adult central nervous system (CNS) is driven by successful differentiation of resident oligodendroglial precursor cells (OPCs) and thus constitutes a neurodegenerative process capable to compensate for functional deficits upon loss of oligodendrocytes and myelin sheaths as it is...

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Bibliographic Details
Main Authors: Peter Göttle, Kira Schichel, Laura Reiche, Luisa Werner, Annika Zink, Alessandro Prigione, Patrick Küry
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
myelin repair
multiple sclerosis (MS)
oligodendrocyte
toll-like receptor
HERV-W
ENV
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.777542/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.777542/full

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