Compensatory Response by Late Embryonic Tubular Epithelium to the Reduction in Pancreatic Progenitors.

Early in pancreatic development, epithelial cells of pancreatic buds function as primary multipotent progenitor cells (1°MPC) that specify all three pancreatic cell lineages, i.e., endocrine, acinar and duct. Bipotent "Trunk" progenitors derived from 1°MPC are implicated in directly regula...

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Bibliographic Details
Main Authors: Wataru Nishimura, Archana Kapoor, Ilham El Khattabi, Wanzhu Jin, Kazuki Yasuda, Susan Bonner-Weir, Arun Sharma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4635002?pdf=render