Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like Mechanism.

The type IX secretion system (T9SS) of Porphyromonas gingivalis secretes proteins possessing a conserved C-terminal domain (CTD) to the cell surface. The C-terminal signal is essential for these proteins to translocate across the outer membrane via the T9SS. On the surface the CTD of these proteins...

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Bibliographic Details
Main Authors: Dhana G Gorasia, Paul D Veith, Dina Chen, Christine A Seers, Helen A Mitchell, Yu-Yen Chen, Michelle D Glew, Stuart G Dashper, Eric C Reynolds
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4560394?pdf=render