SARS-CoV-2 Spike Alterations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus

SARS-CoV-2 Spike Alterations Enhance Pseudoparticle Titers and Replication-Competent VSV-SARS-CoV-2 Virus

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the most recent global pandemic that has caused more than a million deaths around the world. The spike glycoprotein (S) drives the entry and fusion of this virus and is the main determinant of cell tropism. To exp...

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Bibliographic Details
Main Authors: Katherine Elizabeth Havranek, Ariana R. Jimenez, Marissa Danielle Acciani, Maria Fernanda Lay Mendoza, Judith Mary Reyes Ballista, Darren Austin Diaz, Melinda Ann Brindley
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Viruses
Subjects:
SARS-CoV-2
spike
fusion
recombinant VSV
Online Access:https://www.mdpi.com/1999-4915/12/12/1465

Internet

https://www.mdpi.com/1999-4915/12/12/1465

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