History-dependent physiological adaptation to lethal genetic modification under antibiotic exposure

Genetic modifications, such as gene deletion and mutations, could lead to significant changes in physiological states or even cell death. Bacterial cells can adapt to diverse external stresses, such as antibiotic exposure, but can they also adapt to detrimental genetic modification? To address this...

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Bibliographic Details
Main Authors: Yuta Koganezawa, Miki Umetani, Moritoshi Sato, Yuichi Wakamoto
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/74486