Predicting Shine-Dalgarno sequence locations exposes genome annotation errors.
In prokaryotes, Shine-Dalgarno (SD) sequences, nucleotides upstream from start codons on messenger RNAs (mRNAs) that are complementary to ribosomal RNA (rRNA), facilitate the initiation of protein synthesis. The location of SD sequences relative to start codons and the stability of the hybridization...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-05-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1463019?pdf=render |