Early Effects of the Soluble Amyloid β<sub>25-35</sub> Peptide in Rat Cortical Neurons: Modulation of Signal Transduction Mediated by Adenosine and Group I Metabotropic Glutamate Receptors

The amyloid β peptide (Aβ) is a central player in the neuropathology of Alzheimer’s disease (AD). The alteration of Aβ homeostasis may impact the fine-tuning of cell signaling from the very beginning of the disease, when amyloid plaque is not deposited yet. For this reason, primary culture of rat co...

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Bibliographic Details
Main Authors: Carlos Alberto Castillo, Inmaculada Ballesteros-Yáñez, David Agustín León-Navarro, José Luis Albasanz, Mairena Martín
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/12/6577