The Landscape and Therapeutic Targeting of <i>BRCA1</i>, <i>BRCA2</i> and Other DNA Damage Response Genes in Pancreatic Cancer

Genes participating in the cellular response to damaged DNA have an important function to protect genetic information from alterations due to extrinsic and intrinsic cellular insults. In cancer cells, alterations in these genes are a source of genetic instability, which is advantageous for cancer pr...

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Bibliographic Details
Main Authors: Ioannis A. Voutsadakis, Antonia Digklia
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/45/3/135