The Landscape and Therapeutic Targeting of <i>BRCA1</i>, <i>BRCA2</i> and Other DNA Damage Response Genes in Pancreatic Cancer
Genes participating in the cellular response to damaged DNA have an important function to protect genetic information from alterations due to extrinsic and intrinsic cellular insults. In cancer cells, alterations in these genes are a source of genetic instability, which is advantageous for cancer pr...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | Current Issues in Molecular Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/1467-3045/45/3/135 |