Sirtuin 1 alleviates alcoholic liver disease by inhibiting HMGB1 acetylation and translocation

Background Alcoholic liver disease (ALD) encompasses a spectrum of liver disorders resulting from prolonged alcohol consumption and is influenced by factors such as oxidative stress, inflammation, and apoptosis. High Mobility Group Box 1 (HMGB1) plays a pivotal role in ALD due to its involvement in...

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Bibliographic Details
Main Authors: Juan Fu, Wei Deng, Jun Ge, Shengqi Fu, Panpan Li, Huazhi Wu, Jiao Wang, Yi Gao, Hui Gao, Tao Wu
Format: Article
Language:English
Published: PeerJ Inc. 2023-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16480.pdf