dcHiC detects differential compartments across multiple Hi-C datasets

The organisation of mammalian genomes plays a role in many biological processes. Here the authors report dcHiC, a tool which uses a multivariate distance measure to identify changes in compartmentalisation among multiple genome-wide chromatin contact maps, and apply this to different human and mouse...

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Bibliographic Details
Main Authors: Abhijit Chakraborty, Jeffrey G. Wang, Ferhat Ay
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34626-6