What Determines the Class of Immunity an Antigen Induces? A Foundational Question Whose Rational Consideration Has Been Undermined by the Information Overload

Activated CD4 T helper cells are required to activate B cells to produce antibody and CD8 T cells to generate cytotoxic T lymphocytes. In the absence of such help, antigens inactivate B cells and CD8 T cells. Thus, the activation or inactivation of CD4 T cells determines whether immune responses are...

Full description

Bibliographic Details
Main Author: Peter Bretscher
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/9/1253