Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment

Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment

Semaphorin 4D (SEMA4D) is considered a new antitumor target closely related to immune cells. However, understanding the role of SEMA4D in the tumor microenvironment (TME) is limited. In this study, we explored the expression and immune cell infiltration patterns of SEMA4D using multiple bioinformati...

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Bibliographic Details
Main Authors: Shujie Zeng, Zihao Zhang, Chunshui Ye, Jinshen Wang, Changqing Jing, Leping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
SEMA4D
pancancer
tumor microenvironment
immune infiltration
exhaustion of CD8+ T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1171926/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1171926/full

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