Insights into Muscle Contraction Derived from the Effects of Small-Molecular Actomyosin-Modulating Compounds

Insights into Muscle Contraction Derived from the Effects of Small-Molecular Actomyosin-Modulating Compounds

Bottom-up mechanokinetic models predict ensemble function of actin and myosin based on parameter values derived from studies using isolated proteins. To be generally useful, e.g., to analyze disease effects, such models must also be able to predict ensemble function when actomyosin interaction kinet...

Full description

Bibliographic Details
Main Authors: Alf Månsson, Dilson E. Rassier
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
myosin
actin
myosin-active compounds
muscle contraction
mechanokinetic model
statistical model
Online Access:https://www.mdpi.com/1422-0067/23/20/12084

Internet

https://www.mdpi.com/1422-0067/23/20/12084

Similar Items