In Vivo Activity of the Benzothiazinones PBTZ169 and BTZ043 against Nocardia brasiliensis.

BACKGROUND:Mycetoma is a neglected, chronic, and deforming infectious disease caused by fungi and actinomycetes. In Mexico, N. brasiliensis is the predominant etiologic agent. Therapeutic alternatives are necessary because the current drug regimens have several disadvantages. Benzothiazinones (BTZ)...

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Main Authors: Norma Alejandra González-Martínez, Hector Gerardo Lozano-Garza, Jorge Castro-Garza, Alexandra De Osio-Cortez, Javier Vargas-Villarreal, Norma Cavazos-Rocha, Jorge Ocampo-Candiani, Vadim Makarov, Stewart T Cole, Lucio Vera-Cabrera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4608729?pdf=render