The genetic architecture of adaptations to high altitude in Ethiopia.

Although hypoxia is a major stress on physiological processes, several human populations have survived for millennia at high altitudes, suggesting that they have adapted to hypoxic conditions. This hypothesis was recently corroborated by studies of Tibetan highlanders, which showed that polymorphism...

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Bibliographic Details
Main Authors: Gorka Alkorta-Aranburu, Cynthia M Beall, David B Witonsky, Amha Gebremedhin, Jonathan K Pritchard, Anna Di Rienzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003110&type=printable