Deep Profiling of the Aggregated Proteome in Alzheimer’s Disease: From Pathology to Disease Mechanisms

Deep Profiling of the Aggregated Proteome in Alzheimer’s Disease: From Pathology to Disease Mechanisms

Hallmarks of Alzheimer’s disease (AD), a progressive neurodegenerative disease causing dementia, include protein aggregates such as amyloid beta plaques and tau neurofibrillary tangles in a patient’s brain. Understanding the complete composition and structure of protein aggregate...

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Bibliographic Details
Main Authors: Brianna M. Lutz, Junmin Peng
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Proteomes
Subjects:
proteomics
proteome
mass spectrometry
Alzheimer’s disease
protein aggregation
laser capture microdissection
splicing
U1 snRNP
Online Access:https://www.mdpi.com/2227-7382/6/4/46

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https://www.mdpi.com/2227-7382/6/4/46

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