Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1

Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1

Specialized pro-resolving mediators (SPMs), including Maresins (MaR)-1 and 2, contribute to tear film homeostasis and resolve conjunctival inflammation. We investigated MaR2′s signaling pathways in goblet cells (GC) from rat conjunctiva. Agonist-induced [Ca<sup>2+</sup>]<sub>i</...

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Bibliographic Details
Main Authors: Markus V. Olsen, Anne V. Lyngstadaas, Jeffrey A. Bair, Robin R. Hodges, Tor P. Utheim, Charles N. Serhan, Darlene A. Dartt
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
mucin secretion
intracellular Ca<sup>2+</sup>
inflammation
epithelial cell
tear film
eye
Online Access:https://www.mdpi.com/1422-0067/23/11/6233

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https://www.mdpi.com/1422-0067/23/11/6233

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