Investigating the potential of thiazolyl carbohydrazides derivatives as anti-Candida albicans agents: An intuition from molecular modelling, pharmacokinetic evaluation, and molecular docking analysis

Investigating the potential of thiazolyl carbohydrazides derivatives as anti-Candida albicans agents: An intuition from molecular modelling, pharmacokinetic evaluation, and molecular docking analysis

With increasing incidences of antifungal resistance, biofilm formation, and its predilection for vulnerable populations, Candida albicans have been reported to cause a wide range of infections, from superficial skin irritations to life-threatening systemic diseases. Therefore, understanding and addr...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Innocent Benjamin, Chioma U. Benson, Stephen A. Adalikwu, Favour A. Nduoma, Faith O. Akor, Michael O. Odey, Esther C. Ezeani, Isaac A. Anyambula, Maryann A. Odume, Hitler Louis
Format: Artykuł
Język:English
Wydane: Elsevier 2023-12-01
Seria:Chemical Physics Impact
Hasła przedmiotowe:
Thiazolyl carbohydrazides
Antifungal resistance
Candida albicans
DFT
ADMET
Molecular docking
Dostęp online:http://www.sciencedirect.com/science/article/pii/S2667022423001159

Internet

http://www.sciencedirect.com/science/article/pii/S2667022423001159

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