Force generation by molecular-motor powered microtubulebundles; implications for neuronal polarization and growth
The heavily cross-linked microtubule (MT) bundles found in neuronalprocesses play a central role in the initiation, growth andmaturation of axons and dendrites; however, a quantitativeunderstanding of their mechanical function is still lacking. We heredeveloped computer simulations to investigate th...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-11-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00441/full |