Brain injury drives optic glioma formation through neuron-glia signaling

Brain injury drives optic glioma formation through neuron-glia signaling

Abstract Tissue injury and tumorigenesis share many cellular and molecular features, including immune cell (T cells, monocytes) infiltration and inflammatory factor (cytokines, chemokines) elaboration. Their common pathobiology raises the intriguing possibility that brain injury could create a tissu...

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Bibliographic Details
Main Authors: Jit Chatterjee, Joshua P. Koleske, Astoria Chao, Andrew D. Sauerbeck, Ji-Kang Chen, Xuanhe Qi, Megan Ouyang, Lucy G. Boggs, Rujuta Idate, Lara Isabel Marco Y Marquez, Terrence T. Kummer, David H. Gutmann
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Acta Neuropathologica Communications
Subjects:
Optic glioma
Brain tumor
Cytokine
Traumatic brain injury
Optic nerve crush
Microglia
Online Access:https://doi.org/10.1186/s40478-024-01735-w

Internet

https://doi.org/10.1186/s40478-024-01735-w

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