Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector.

Legionella pneumophila is an intracellular pathogen responsible for Legionnaires' disease. This bacterium uses the Dot/Icm type IV secretion system to inject a large number of bacterial proteins into host cells to facilitate the biogenesis of a phagosome permissive for its intracellular growth....

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Bibliographic Details
Main Authors: Li Xu, Xihui Shen, Andrew Bryan, Simran Banga, Michele S Swanson, Zhao-Qing Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2841630?pdf=render