The role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channels
Protein-folding diseases are an ongoing medical challenge. Many diseases within this group are genetically determined, and have no known cure. Among the examples in which the underlying cellular and molecular mechanisms are well understood are diseases driven by misfolding of transmembrane proteins...
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| Format: | Article |
| Language: | English |
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The Company of Biologists
2014-03-01
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| Series: | Disease Models & Mechanisms |
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| Online Access: | http://dmm.biologists.org/content/7/3/319 |