Skeletal muscle satellite cells, mitochondria and microRNAs: their involvement in the pathogenesis of ALS

Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND), is a fatal motor neurone disorder. It results in progressive degeneration and death of upper and lower motor neurones, protein aggregation, severe muscle atrophy and respiratory insufficiency. Median survival with ALS is...

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Bibliographic Details
Main Authors: Stavroula Tsitkanou, Paul Adrian Della Gatta, Aaron Paul Russell
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00403/full