SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis

SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis

Introduction: Atherosclerotic complications represent the leading cause of cardiovascular mortality globally. Dysfunction of endothelial cells (ECs) often initiates the pathological events in atherosclerosis. Objectives: In this study, we sought to investigate the transcriptional profile of atherosc...

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Bibliographic Details
Main Authors: Chak Kwong Cheng, Xiao Lin, Yujie Pu, Joyce Ka Yu Tse, Yu Wang, Cheng-Lin Zhang, Xiaoyun Cao, Chi Wai Lau, Juan Huang, Lei He, Jiang-Yun Luo, Yu-Tsung Shih, Song Wan, Chi Fai Ng, Li Wang, Ronald Ching Wan Ma, Jeng-Jiann Chiu, Ting Fung Chan, Xiao Yu Tian, Yu Huang
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Advanced Research
Subjects:
Atherosclerosis
EndoMT
Endothelial cells
Shear stress
Single-cell RNA sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222000613

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http://www.sciencedirect.com/science/article/pii/S2090123222000613

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