Receptor tyrosine kinases Tyro3, Axl, and Mertk differentially contribute to antibody-induced arthritis

Abstract Tyro3, Axl, and Mertk (abbreviated TAMs) comprise a family of homologous type 1 receptor tyrosine kinases (RTKs) that have been implicated as inhibitory receptors that dampen inflammation, but their roles in the pathogenesis of rheumatoid arthritis remains understudied. Here, to investigate...

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Bibliographic Details
Main Authors: Liang Gao, Chao He, Aizhen Yang, Haibin Zhou, Qingxian Lu, Raymond B. Birge, Yi Wu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-023-01133-0