Insights into the role of endonuclease V in RNA metabolism in Trypanosoma brucei

Abstract Inosine may arise in DNA as a result of oxidative deamination of adenine or misincorporation of deoxyinosine triphosphate during replication. On the other hand, the occurrence of inosine in RNA is considered a normal and essential modification induced by specific adenosine deaminases acting...

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Bibliographic Details
Main Authors: Daniel García-Caballero, Guiomar Pérez-Moreno, Antonio M. Estévez, Luis Miguel Ruíz-Pérez, Antonio E. Vidal, Dolores González-Pacanowska
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08910-1