Necdin protects embryonic motoneurons from programmed cell death.

NECDIN belongs to the type II Melanoma Associated Antigen Gene Expression gene family and is located in the Prader-Willi Syndrome (PWS) critical region. Necdin-deficient mice develop symptoms of PWS, including a sensory and motor deficit. However, the mechanisms underlying the motor deficit remain e...

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Bibliographic Details
Main Authors: Julianne Aebischer, Rachel Sturny, David Andrieu, Anne Rieusset, Fabienne Schaller, Sandrine Geib, Cédric Raoul, Françoise Muscatelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3166279?pdf=render