Semaphorin‐3C signals through Neuropilin‐1 and PlexinD1 receptors to inhibit pathological angiogenesis

Semaphorin‐3C signals through Neuropilin‐1 and PlexinD1 receptors to inhibit pathological angiogenesis

Abstract Retinopathy of prematurity causes visual impairment due to destructive neoangiogenesis after degeneration of the retinal microvasculature. This study was aimed at analyzing whether local delivery of Semaphorin‐3C (Sema3C) suppresses pathological retinal angiogenesis. Sema3C exerted potent i...

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Bibliographic Details
Main Authors: Wan‐Jen Yang, Junhao Hu, Akiyoshi Uemura, Fabian Tetzlaff, Hellmut G Augustin, Andreas Fischer
Format: Article
Language:English
Published: Springer Nature 2015-07-01
Series:EMBO Molecular Medicine
Subjects:
angiogenesis
semaphorin
retinopathy of prematurity
Sema3C
Online Access:https://doi.org/10.15252/emmm.201404922

Internet

https://doi.org/10.15252/emmm.201404922

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