BRCA1 Accelerates CtIP-Mediated DNA-End Resection
DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In higher eukaryotes, CtIP regulates resection by integrating cellular signals via its posttranslational modifications and protein-protein interactions, including cell-cycle-controlled i...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-10-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714007682 |