The spatiotemporal and paradoxical roles of NRF2 in renal toxicity and kidney diseases

The spatiotemporal and paradoxical roles of NRF2 in renal toxicity and kidney diseases

Over 10% of the global population is at risk to kidney disorders. Nuclear factor erythroid-derived 2-related factor 2 (NRF2), a pivotal regulator of redox homeostasis, orchestrates antioxidant response that effectively counters oxidative stress and inflammatory response in a variety of acute pathoph...

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Bibliographic Details
Main Authors: Yiying Bian, Jize Dong, Zhengsheng Zhou, Hua Zhou, Yuanyuan Xu, Qiang Zhang, Chengjie Chen, Jingbo Pi
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Redox Biology
Subjects:
NRF2
Oxidative stress
Renal toxicity
Kidney diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724004543

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http://www.sciencedirect.com/science/article/pii/S2213231724004543

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