Rhein Suppresses Lung Inflammatory Injury Induced by Human Respiratory Syncytial Virus Through Inhibiting NLRP3 Inflammasome Activation via NF-κB Pathway in Mice

Rhein Suppresses Lung Inflammatory Injury Induced by Human Respiratory Syncytial Virus Through Inhibiting NLRP3 Inflammasome Activation via NF-κB Pathway in Mice

Rhein is one of active anthraquinone components in traditional Chinese herbal medicine Rheum palmatum L., possessing anti-inflammatory, antioxidant, antitumor, antiviral, and hepatoprotective activities. Human respiratory syncytial virus (RSV), a common virus, is able to result in pneumonia and bron...

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Bibliographic Details
Main Authors: Cunsi Shen, Zhengguang Zhang, Tong Xie, Jianjian Ji, Jianya Xu, Lili Lin, Jing Yan, An Kang, Qigang Dai, Yingmei Dong, Jinjun Shan, Shouchuan Wang, Xia Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
rhein
respiratory syncytial virus infection
lung inflammation
pro-inflammatory cytokine
tissue damage
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01600/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01600/full

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