Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking

Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking

Humans and other vertebrates define body axis left-right asymmetry in the early stages of embryo development. The mechanism behind left-right establishment is not fully understood. Symmetry breaking occurs in a dedicated organ called the left-right organizer (LRO) and involves motile cilia generatin...

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Bibliographic Details
Main Authors: Pedro Sampaio, Sara Pestana, Catarina Bota, Adán Guerrero, Ivo A Telley, David Smith, Susana Santos Lopes
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
left-right
Kupffer's vesicle
fluid flow
motile cilia
mechanosensory hypothesis
chemosensory hypothesis
Online Access:https://elifesciences.org/articles/83861

Internet

https://elifesciences.org/articles/83861

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