New Clox Systems for rapid and efficient gene disruption in Candida albicans.

Precise genome modification is essential for the molecular dissection of Candida albicans, and is yielding invaluable information about the roles of specific gene functions in this major fungal pathogen of humans. C. albicans is naturally diploid, unable to undergo meiosis, and utilizes a non-canoni...

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Bibliographic Details
Main Authors: Shahida Shahana, Delma S Childers, Elizabeth R Ballou, Iryna Bohovych, Frank C Odds, Neil A R Gow, Alistair J P Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4062495?pdf=render