A hybrid RNA-protein biosensor for high-throughput screening of adenosylcobalamin biosynthesis

Genetically encoded circuits have been successfully utilized to assess and characterize target variants with desirable traits from large mutant libraries. Adenosylcobalamin is an essential coenzyme that is required in many intracellular physiological reactions and is widely used in the pharmaceutica...

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Bibliographic Details
Main Authors: Xia Yang, Huiying Wang, Dongqin Ding, Huan Fang, Huina Dong, Dawei Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-09-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X24000590