Tripartite motif 31 drives gastric cancer cell proliferation and invasion through activating the Wnt/β-catenin pathway by regulating Axin1 protein stability

Abstract Mounting evidence has proposed the importance of the Wnt/β-catenin pathway and tripartite motif 31 (TRIM31) in certain malignancies. Our research aimed to clarify the correlation between aberrant TRIM31 expression and the Wnt/β-catenin pathway during gastric cancer (GC) oncogenesis and deve...

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Bibliographic Details
Main Authors: Qi Feng, Fengting Nie, Lihong Gan, Xianpin Wei, Peng Liu, Hui Liu, Kaige Zhang, Ziling Fang, Heng Wang, Nian Fang
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47139-z