PPARA ameliorates sepsis-induced myocardial injury via promoting macrophage M2 polarization by interacting with DUSP1

Background: The morbidity and mortality of sepsis are increasing year by year. Statistically, 40–50% of patients with sepsis have concomitant myocardial injury, and its mortality rate is higher than that of patients with sepsis only. Therefore, it is of great significance to elucidate the mechanism...

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Bibliographic Details
Main Authors: Li Cheng, Dezhi Liu, Shanglan Gao
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320424000798