Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again

Ras is the most frequently mutated oncogene and recent drug development efforts have spurred significant new research interest. Here we review progress toward understanding how Ras functions in nanoscale, proteo-lipid signaling complexes on the plasma membrane, called nanoclusters. We discuss how G-...

Full description

Bibliographic Details
Main Authors: Daniel Abankwa, Alemayehu A. Gorfe
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/11/1522