Practical identifiability in the frame of nonlinear mixed effects models: the example of the in vitro erythropoiesis

Abstract Background Nonlinear mixed effects models provide a way to mathematically describe experimental data involving a lot of inter-individual heterogeneity. In order to assess their practical identifiability and estimate confidence intervals for their parameters, most mixed effects modelling pro...

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Bibliographic Details
Main Authors: Ronan Duchesne, Anissa Guillemin, Olivier Gandrillon, Fabien Crauste
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04373-4