The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages

The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages

IntroductionMacrophages significantly contribute to the regulation of vessel formation under physiological and pathological conditions. Although the angiogenesis-regulating role of alternatively polarized macrophages is quite controversial, a growing number of evidence shows that they can participat...

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Main Authors: Apolka Domokos, Zsofia Varga, Karoly Jambrovics, Noemí Caballero-Sánchez, Eniko Szabo, Gergely Nagy, Beata Scholtz, Laszlo Halasz, Eszter Varadi, Krisztian P. Bene, Anett Mazlo, Attila Bacsi, Viktoria Jeney, Gabor J. Szebeni, Laszlo Nagy, Zsolt Czimmerer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
macrophage
IL-4
VEGFA
FLT1
hypoxia
transcriptional regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1168635/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1168635/full

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