Stable Signal Peptides and the Response to Secretion Stress in <italic toggle="yes">Staphylococcus aureus</italic>

ABSTRACT Protein secretion is essential, but how it is managed is poorly understood. In bacteria, most secreted proteins require release from the outer surface of the cytoplasmic membrane by type I signal peptidase (SPase), which cleaves the mature protein from its membrane-bound N-terminal signal p...

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Bibliographic Details
Main Authors: Arryn Craney, Floyd E. Romesberg
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01507-17