Generation of truncated derivatives through in silico enzymatic digest of peptide GV30 target MRSA both in vitro and in vivo

Generation of truncated derivatives through in silico enzymatic digest of peptide GV30 target MRSA both in vitro and in vivo

Methicillin-resistant Staphylococcus aureus (MRSA) causing serious hospital-acquired infections and skin infections has become a “superbug” in clinical treatment. Although the clinical treatment of MRSA is continuously improving, due to its unceasing global spread, MRSA has produced much heated disc...

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Bibliographic Details
Main Authors: Yingxue Ma, Aifang Yao, Xiaoling Chen, Lei Wang, Chengbang Ma, Xinping Xi, Tianbao Chen, Chris Shaw, Mei Zhou
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Methicillin-resistant Staphylococcus aureus
Antimicrobial peptides
Truncated derivatives
PeptideCutter tool
Antibacterial effect
Toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021003706

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http://www.sciencedirect.com/science/article/pii/S2001037021003706

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